Stems relatively pubescent at nodes, usually more than 15 hairs per 0.1 sq. mm at most pubescent portion (excluding angle of petiole with stem). Leaf blades 10 cm or more usually having fewer than 5 lobes; smaller blades (ca. 5 cm) often with no more than 3 easily visible veins branching off midrib (excluding proximal branches); surfaces abaxially conspicuously pubescent, more than 100 hairs per cm on length of medial midrib, more than 25 glands per 10 sq. mm between veins, hairs present between veins. Moist thickets, woods; 0-1000 m; Ark., Ill., Ind., Iowa, Kans., Md., Minn., Mo., Nebr., N.Y., N.C., Ohio, Okla., Pa., Va. Humulus lupulu s var. pubescens intergrades with other varieties. It is found primarily in the midwestern United States.